<> Then, users will right click on the same curve to display a menu. 1 0 obj In DSC, the heat flow to and from a sam-ple and a reference material is measured as a function of temperature as the sam-ple is heated, cooled or held at constant temperature. A We must first list all pertinent information we know about the sample before we can analyze the data. The higher the thermal transition midpoint (Tm), the more stable the molecule. In Draft View, the page automatically sizes to fill the graph window. Differential Scanning Calorimetry (DSC) Differential Scanning Calorimetry (DSC) is an analytical technique which measures the heat flow into or out of a sample as a function of time and/or temperature. Ease-of-use in this case refers to sample preparation and experimental setup, as well as interpretation of the results. Generally, the non-isothermal DSC is used for the identification of neat basic polymers as well as the determination of their purity and stability. Introduction Epoxy adhesives are often used as adhesives and fillers for materials such as metal, glass, ceramic, and plastic. 5 Q What can we learn from this TGA Thermal Curve? A biomolecule in solution is in equilibrium between its native (folded) and denatured (unfolded) conformations. It is also used to determine the change in heat capacity (ΔCp) of denaturation. The curve should now be cut into Similarly, "perspective" should not be added to two-dimensional charts and graphs, as it impedes quick and correct interpretation. The output from a DTA is temperature … They should be read in conjunction with more comprehensive treatments, some of which are listed at the end. ; so be careful handling the sample, wear eye protection • It is hygroscopic (it absorbs or attracts moisture from the air). Data Interpretation: The output of a DSC is a plot of heat flux (rate) versus temperature at a specified temperature ramp rate. Both the sample and reference are maintained at nearly the same temperature throughout the experiment. Polyethylene terephthalate or PETE, is a commonly used plastic in food packaging, including beverage bottles: PETE is a semi-crystalline polymer. For example, ... • The bottom right frame shows a live graph of your data once the test has started. To obtain the graph of T m x 1/F from the DSC curve, some points, normally within the region between 10 and 50% of the peak, are evaluated. 3 DSC Training Course Second Generation Q-Series™ DSCs Q2000 Q200 AutoQ20 A sample of known mass is heated or cooled and the changes in its heat capacity are tracked as changes in the heat flow. After molding, the plastic has crystalline and amorphous regions. The DSC graph showing "ACV-1" is for a pure drug while "PM-1" is the graph of a physical mixture of that drug along with two other polymers. DSC Measurements of Epoxy Adhesives 1. One general limitation depicted is the possibility of multiple interpretations of a single measurement signal which sometimes makes definite identification difficult. 1215 0 obj <>stream TA DSC and Mettler DSC) and the power compensated DSC (Perkin-Elmer system). Common materials include foods, pharmaceuticals, electronic materials, polymers, ceramics, organic and inorganic compounds, even biological organisms… This is a … The DSC Analysis Technique. DSC can elucidate the factors that contribute to the folding and stability o… H33�m�� d�0����(g�0 �}� Interpretation and analysis of DSC data may be difficult for some samples. %PDF-1.7 For example, tables do not need to be boxed in with lines surrounding each value. It requires a considerable amount of experience in thermal The current field of thermal analysis is both diverse and dynamic. G�YecJ0�[:&ႉ�zq6s>Xl����%J�_S���F��,R�"��? obscure the main message of the table or graph. stream DSC allows you to detect endothermic This tool features many powerful techniques for studying polymer thermal properties and provides essential information to the polymer industry and end users of polymer-based products. 0 The peak temperature is an important experimental value in DSC measurements. Draft View has the fastest screen update of the four view modes. h�bbd```b``�".�HF��"Y��L�`v3X�$�T �� ��L6�E��Un�D�Șb��lr*��Q�ˀ$���R{H��T[q-��9g�b+��؊ ���#�����D*�I5��~�1012�Ȃ}��H���ߚ� ��� <>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> 3 DSC Instructions Two types of DSC instruments are widely used: the heat ux DSC (eg. The article explains the reasons for these differences and discusses the possibilities for … <>/Metadata 650 0 R/ViewerPreferences 651 0 R>> Differential scanning calorimetry (DSC) measures the energy absorbed (endotherm) or produced ... curing peak on the DSC curve. Thus, DSC curve could be used to infer about the presence of a particular compounds and its thermal behaviour. endstream endobj 1166 0 obj <>/Metadata 66 0 R/OpenAction 1167 0 R/PageLayout/SinglePage/Pages 1163 0 R/StructTreeRoot 93 0 R/Type/Catalog/ViewerPreferences<>>> endobj 1167 0 obj <> endobj 1168 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/Properties<>>>/XObject<>>>/Rotate 0/StructParents 3/TrimBox[0.0 0.0 594.0 792.0]/Type/Page>> endobj 1169 0 obj <>stream h�b```b``�g`c`�� ̀ ��@Q������ln|:5qe��F�m^00�)2h>x��TH��^��K�b�U�.+ͪJ�-X2���H�c�U�:/�)'�^�X��6o�OP}WӤ̗&'w5)O�����д�� -l�B�;:��+@��b� �Ł���B|n@Z ���~ad�˨�`��郜�{�6�ë= DSC Data Analysis in Origin ... other objects in a graph window that reside in the gray area of the page are not visible in Window View mode. Differential scanning calorimetry is a specific type of calorimetry including both a sample substance and a reference substance, residing in separate chambers. … DSC Although DSC is a simple, convenient and fast technique to measure lipid oxidation, some recommended guidelines should be considered to obtain reliable and reproducible results. 2 DSC Training Course 2900 Series DSC’s DSC 2010 DSC 2910 DSC 2920 DSC Training Course Q1000 Q100 Q10 First Generation Q Series™ DSCs. This allows the detection of transitions such as melts, endobj endobj From this menu select the “Split Into Segments” option. 1202 0 obj <>/Filter/FlateDecode/ID[<8396A40228C5ED45AC5751051A60CB23>]/Index[1165 51]/Info 1164 0 R/Length 156/Prev 1324854/Root 1166 0 R/Size 1216/Type/XRef/W[1 3 1]>>stream Differential scanning calorimetry (DSC) is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. 1.5 DSC Differential Scanning Calorimetry. Differential Scanning Calorimetry (DSC) – provides information about thermal changes that do not involve a change in sample mass11 – more commonly used technique than TGA – Two basic types of DSC instruments: heat-flux and power compensation 1Haines, P. J. DSC-TGA (SDT): The Technique Q600 SDT Simultaneous DSC-TGA: Measures heat flow and weight changes simultaneously Simultaneous DSC-TGA measures both heat flow and weight changes in a material as a function of temperature or time in a controlled atmosphere. %PDF-1.6 %���� During curing, the epoxy group starts a polymerization reaction, cross-links and 9. In this case of calcium carbonate we know: • CaCO 3 is an irritant! hެVmo�H�++ݗT�t��k�T!M��B���C|p`�Ʀ�I����,���&��xdz3���>;FH�gBr��H �)�i�2m����)�L@���z �A`I�LD�0�b(�4ͤ�!����8q� fL�1c��É�l�O�l�j��i�����D�^��䒸tRG���nq��t��ˋ�p�R�mw��]��뿈��C��e-�g�!�\���/�$� 8. The measurement signal is the energy absorbed by or released by the sample in milliwatts. DSC analysis is used to measure melting temperature, heat of fusion, latent heat of melting, reaction energy and temperature, glass transition temperature, crystalline phase transition temperature and energy, precipitation energy and temperature, denaturization temperatures, oxidation induction times, and specific heat or heat capacity. endobj Interpreting DSC curves Part 1: Dynamic measurements The art of interpreting curves has yet to be integrated into commercially available com-puter programs. The heat flux can be converted to CP by dividing by the constant rate of temperature change. There are, however, some common DSC events/ transitions that can be the cause of less than optimum results and/or misinterpretation. 3.1 Heat Flux DSC In a heat ux DSC system the sample and reference are heated at the same rate from a single heating source as shown in Figure 6. Plots showing differences in heat flow between a sample and reference, as a function of time Differential scanning calorimetry• This technique is used to study what happens to polymers/samples upon heating• It is used to study thermal transitions of a polymer/sample (the changes that take place on heating) – For example: • The melting of a crystalline polymer • The glass transition • The crystallization 3. x��UQo�0~���G�Vc�A�*am�DMS5E}�)��:�1WS��lHP���F��qw>�w��ֲ|�WNO�P�|��x���m�wv��-�E�.�\���N��6]�CQ��A4�ᗁ&� (\�ԅ�n?Ae�(3���s! 1165 0 obj <> endobj One of the tools proven to address these needs is differential scanning calorimetry (DSC). Determination of the melting temperature, heat of fusion, and purity analysis of different samples of zidovudine (AZT) using DSC 39 F- fraction of sample melted at T m, R- gas constant, 8.314 J mol-1 deg. 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