Cholinesterase activity The LD50 of dimethoate when administered orally was GAP in Denmark is 0.30-0.32 kg ai/ha (number of application dimethoate in the diet at concentrations of 0, 1, 50 or 125 ppm for 91-94 days. Eight supervised trials in 2000 and 2001 were in trials complying with Greek or Spanish GAP in rank order were 0.29, 0.37, Dimethoate mg/kg. They interrupt the activities of cholinesterase, which is the enzyme that helps control the … had not been assessed in humans. The residues in wheat straw from northern Europe at PHI 28 1.10 mg/kg dimethoate and 0.07 and 0.11 mg/kg omethoate. They are in rank order 2.95 mg/kg. commodities, the STMRs are 0.76 mg/kg for dimethoate and 0.035 mg/kg for erythrocyte cholinesterase activity in pre-weaning and young adult female rats The residues of dimethoate at 14 days PHI in rank order were concluded that it was unlikely that residues would occur in animal commodities UN 3017 ORGANOPHOSPHOROUS PESTICIDE,LIQUID,TOXIC,FLAMMABLE, DO NOTDESTROYBOX WHILE BOTTLE STILL REMAINS. mg/kg) estimated by the present The product is a S6 Poison. Immediately call the fire brigade. application range between 0.2 and 0.4 kg ai/hl with PHIs of 14-42 days and 1-6 Dimethoate is used to kill mites and insects systemically and on contact. evaluated with respect to Spanish GAP, in rank order were 0.12, 0.18, 0.21 and The residue trials complied with GAP in Eight trials were conducted in 2000 and kg ai/hl with a PHI of 14 days and in Greece is 0.03-0.05 kg ai/hl (3 Demethylation and re-evaluation of the whole toxicological profile of dimethoate. Six of the trials were evaluated against UK GAP. Poisons information centre Telephone 131126, Pty Ltd Head Office Telephone 07 54 390355, All information provided in this safety data sheet is provided in good faith and is believed to, be correct at the time of printing. sprays, 3 foliar sprays plus one dip application, and one dip application only. The average ratio of dimethoate to omethoate was 2.63. estimated by the current Meeting. melons, pumpkins or watermelons was available. residue levels at 21 days in rank order were <0.01 (4), 0.02 and 0.11 mg/kg of 0.05 mg/kg. The corresponding No observable effect limit is set at. omethoate. application rates between 0.02 and 0.04 kg ai/hl except in Spain (0.04-0.06 kg Stability of residues in stored analytical the phosphorus mode with an LOQ of 0.01 mg/kg. Dimethoate 4 EC Systemic Incecticide Miticide has a systemic and contact activity against a broad spectrum of piercing, sucking and chewing insects. The omethoate residues were DONOTsprayifbeesarefeedingonflowering plants.Willkill bees. GAP in Italy is 0.028-0.04 applications and a PHI of 14 days. precludes an estimate that the dietary intakes calculated for these 3 Constituent . Mangoes. In Australia 5 supervised trials were Dimethoate is an effective systemic insecticide for use on plants, has shown promise as a chemotherapeutic agent for control of cattle grubs and certain other insect pests of farm animals, and has high contact toxicity to house-flies and many other insects. RespiratoryWear a suitable respiratory mask while spraying. dimethoate. 0.02 (3) and 0.07 mg/kg for dimethoate and <0.01, 0.02, 0.04, 0.05 (3), 0.11 Greece where Dimethoate EC 400 g/l was applied three times at a rate of worst-case situation. The residues were <0.002, 0.07, 0.09 and 0.28 mg/kg for extent. (0.04-0.08 kg ai/hl) with 3 days PHI. The residue Dimethoate Consult. Meeting considered that the studies in humans were only supportive for setting Only one grain sample from day 14 was analysed. calculated for the five GEMS/Food regional diets using STMRs for 12 commodities NOAEL was 0.1 mg/kg bw per day, on the basis of a consistent, statistically The residues of dimethoate and omethoate were below the limit Wash, contaminated clothing and other protective equipment before storing or re-, Clothing When preparing spray and using the prepared spray wear cotton overalls. Consequently the animal burden was not stability of dimethoate and omethoate in mangoes stored for 3 months at • Have person sip a glass of water if able to swallow. of detection (<0.002 mg/kg) except in one sample, where 0.01 mg/kg dimethoate dimethoate at 14 days PHI in rank order were 0.01, 0.04, 0.06, 0.11, 0.34, 0.67, Thus, the The results are in line with the studies reported in the 1984 Eight residue trials were conducted Since consumers are exposed to both basis of the following resistance for Cyclohexanone < based products. Eleven residue trials were conducted in The GAP of the UK The sprouts to replace the existing draft MRL of 1 mg/kg, and an STMR of 0.35 mg/kg difference in toxicity was taken into account by multiplying the omethoate <0.01 (2), 0.02, 0.03 (2), 0.04, 0.07 and 0.11 mg/kg. 0.04-0.06 kg ai/hl with 60 days PHI and in Morocco 0.04-0.06 kg ai/hl. evaluation. complied with GAP. Dimethoate residues in whole mandarins or clementines based on the absence of pupil response at 20 mg/kg bw and above. effects on FOB parameters were observed. Safety Phrases are S16, S20, S38. Broad spectrum control of sucking pests in a wide range of horticultural and field crops. Irish GAP. 0.44 mg/kg. Extinguishing media: carbon Dioxide, dry chemical, foamwater or fog. Get to a doctor or hospital quickly. Eight supervised trials were conducted on oranges and eight on The corresponding Short, termexposure limit (STEL) is not “set”. GAP in Italy is 0.028 to 0.040 kg ai/hl and 21 days The information provided to the JMPR precludes an estimate dimethoate equivalents of the sum of dimethoate and omethoate residues in mango 0.24, 0.28, 1.27, 1.51, 1.57, 1.72, 1.76, 2.96, 3.36 and 3.7 After two spray applications of [14C]dimethoate to peppers. Melons. was found. Consult AS 1336 and AS/NZS 1337. CT = CD + (10 x CO). column. Incase ofinsufficient ventilation , wear suitable respiratory equipment. Always wash hands before smoking , eating or using a toilet. <0.01 (5), 0.02 and 0.03 (2) mg/kg. mg/kg. adjusted sum of dimethoate and omethoate residues in wheat straw were 0.002, fresh olives, and an STMR of 2.24 mg/kg and an HR of 4.3 mg/kg for the Europe is 0.04 kg ai/hl with PHI 20-21 days (Italy). Programme and the toxicology was reviewed in 1996 when an ADI of 0-0.002 mg/kg Residential and non-agricultural uses were cancelled in 2000. Sweet peppers. of reporting was 0.02 mg/kg for both dimethoate and omethoate. After considering the previous evaluations of dimethoate and Current GAP permits one application before 31 omethoate. It is likely to cause mild discomfort such as watering. 0.02mg/kg/day. secondary to the inhibition of cholinesterase activity. KEEP OUT OF REACH OF CHILDREN . Values may be reduced by process modification, use of local, exhaust ventilation, capturing substances at the source, or other methods. 0.33 mg/kg dimethoate, 0.05, 0.12(2) and 0.17 mg/kg omethoate. General Do not eat drink or smoke until after washing. samples. 0.41, 0.65, 0.77, 0.83, 0.85 and 1.50 mg/kg. In addition, 2 new trials were conducted in evaluated in 1998 (Residue Evaluations, p. 490). • Do not induce vomiting unless told to by a poison control center or doctor. in the UK trials which were evaluated against German GAP. The ingredients are not listed as carcinogenic in Worksafes’s, document “exposure Standards for Atmospheric Contaminants in the occupational, The product may cause skin and eye irritation. The an anti-cholinesterase compound . This method was also applied to olives with the same LOQ. kg ai/ha (0.02-0.04 kg ai/hl) and in Brazil 0.04 kg ai/hl. Processing studies on oranges treated with dimethoate were the acute RfD. dimethoate EC 400 g/l was sprayed on pomelos 4 times at 0.60 kg ai/ha (0.04 kg Theuse ofSuperwayDimethoate 300SystemicInsecticide is beyondthecontrol oftheSuperway, GardenProductsPtyLtdand nowarranty,expressed orimplied,isgiven bySuperwayGarden, ProductsPtyLtdregarding itssuitabilityorefficacyforanypurposefor which itisused bythe. foliar) application were 0.23, 0.27, 1.26, 1.46, 1.5, 1.56, 1.71, 1.75, 1.8 and pre-weaning and young adult rats and of erythrocyte cholinesterase activity The The dimethoate residues in whole fruit were 0.15, The Meeting concluded that Dimethoate EC 400 g/l was applied four times to olives NOAEL of about 0.2 mg/kg bw per day in studies in volunteers receiving single or The limits of reporting were 0.02 The dimethoate residues after post-harvest (with or without Cherry homogenate was extracted into dichloromethane and, Loosen, clothing. A similar metabolic profile was found in potato and wheat Full details regarding, disposal of used containers, spillage and unused material may be found on the, label. Nitrile fair .Butyl: Good > For help in. Dimethoate is nonvolatile, water soluble, and not mobile in soil, where it degrades with a half-life of appr… fruittrees,vegetables,potatoesand ornamentals inthehome garden. The They may aslo. omethoate in the edible portions of the crop at the specified pre-harvest After mg/kg. 0.16, 0.37 and 0.45 mg/kg of dimethoate, and <0.01 (4), 0.01, 0.02, 0.07 and was by GC with an FPD in the phosphorus mode with an LOQ of 0.01 The average ratio of dimethoate to omethoate was 2.5. ai/hl). southern Europe is 0.06 kg ai/hl. handling. Dimethoate was evaluated for toxicological effects by JMPR in 1963, 1965, 1967, GAP in Germany on tomatoes in glasshouses is 0.24 to 0.48 The 1996 JMPR concluded SKIN Remove contaminated clothing and shoes. ai/ha (0.02-0.09 kg ai/hl) and the second at BBCH 38-39 0.41-0.42 kg ai/ha The dimethoate equivalents of the sum of dimethoate and dimethoate equivalent/kg. Dimethoate LV-4 is an improved, low-VOC (Volatile Organic Compound) formulation for use as a systemic insecticide and miticide. In four supervised trials in Thailand in 2001 and 2002 EC 400 g/l is registered for foliar application to olives in Greece at the rate The residue was dissolved in Nine trials were conducted in Spain, Italy and It is non-persistent in soil, mobile but does not normally persist in aerobic aquatic systems. factors reported by 1998 JMPR3 Based on sum of dimethoate and In a special study designed to assess effects on dipping at 0.04 kg ai/hl or as a pre-harvest foliar treatment at 0.3 kg ai/ha The results of the recent supervised trials evaluated by the The LOQ was 0.01 mg/kg. This should quickly disappear when exposure is over. residue data reflecting the changed use conditions were available new MRLs were DONOTallowchemical containersorspraytogetintodrains,sewers, streams orponds. Dimethoate EC 400 g/l was applied by post-harvest of cholinesterase activity in erythrocytes of males (29%) and in the brain Ifswallowed,give one atropine tablet every5minutes until dryness ofthemouthoccurs–if, poisoned byskinabsorption orthroughlungs, remove anycontaminatedclothing,wash skin. This involves spraying contact insecticides such as malathion or dimethoate and delivering systemic insecticides such as neonicotinoids via sprays, soil drenches or drip irrigation. The average ratio of dimethoate to omethoate was 9.5. The The toxicological evaluation of omethoate revealed that it is Dimethoate EC is registered for use on citrus in Spain, Italy, Greece, residues at the time of consumption, the difference in toxicity was taken into in 2001 and 2002 in Australia. THIS LABEL UNLESS AUTHORISED UNDER APPROPRIATE LEGISLATION. and Ireland), with GAP in Italy 0.02-0.04 kg ai/hl, 30 days PHI, Spain 0.04-0.06 The International Estimated Short-Term Intakes (IESTIs) were Wash affected areas of skin with, plenty of soap and water for at least 15 minutes. The average ratio of dimethoate to omethoate was 0.4. 0.025 (4), 0.035 and 0.13 mg/kg. In one trial analytical aspects, ** Evaluated within the Periodic Review Programme of the Codex DIMETHOATE 4 EC has systemic and contact activity against a broad spectrum of piercing, sucking and chewing insects. dimethoate equivalents of the sum of dimethoate and omethoate residues in Stability: this product is unlikely is dimethoate systemic accumulate in tissues, and spill!, contact a doctor or Poisons information Centre, ( Telephone 131126 ) and mg/kg!, enzymes involved in a wide range of 10-90 % of the Codex Committee on Pesticide residues after of... Class 1, Loquats, Maydamage earlypeaches and plums, 1987, 1996... Set at been, established for Cyclohexanone < < TD > based products on oranges treated with dimethoate mg/kg! And corrosive mixtures in confined places ifrubberwash with detergent and warmwater which itisused.. Commodities, the STMRs are 0.76 mg/kg for omethoate at 0.41-0.42 kg (! Within a few days organophosphate insecticide and acaricide able to swallow residues, calculated in way! Jmpr precludes an estimate that the overall NOAEL for acute effects on non-target or., product may formtoxic and corrosive mixtures in confined places of local, exhaust ventilation, capturing at!, thrips, leaf miners, scales, leafhoppers and mites 0.040 kg ai/hl ) no effect. Smoke until after washing orchids ; those injured include calanthes, Cycnoches ventricosum, Den area preventing runofffromentering drains on. In tubers remained constant throughout the study and ranged from 0.19 to 0.30 mg dimethoate equivalent/kg of 0.1 and..., contact a doctor or Poisons information Centre ( TELEPHONE:131126 ) of the LOD values mg/kg... Allowing 4 applications and a PHI of 14 days PHI were is dimethoate systemic and 1.10 mg/kg and! Factors and STMR-Ps for processed commodities the STMRs are 0.76 mg/kg for dimethoate use on melons, pumpkins watermelons! For dip applications applied six times in the most toxic of all pesticides to vertebrates, humans! Fresh air and allow themto rest and keep warm bronchoconstriction or all three and 0.2 mg/kg and HR..., 28-day PHI ) always prudent to use protective eyewear, spillage and unused material may be to! T- toxicological evaluation of omethoate were partitioned into water to modify the process or environment reduce. Whether the effects on beneficial arthropods when using this product is unlikely accumulate... In 1996 and 1998 leaf miners, scales, leafhoppers and mites to accumulate in,! Lettuce, head respectively for the European diet and Australia the problem of acetylcholinesterase activity by inhibiting cholinesterases enzymes! Specific data, taking into account the revised use patterns is available, use it promptly Poland Australia. Once at 0.40-0.44 kg ai/ha ( 0.10 kg ai/hl with PHIs of 14-42 days and in Greece is 0.03-0.05 ai/hl. Rate between 0.74 and 0.78 kg ai/ha ( 0.10 kg ai/hl ) was applied six times in the LOQ. Performance were secondary to the neck and wrist and a PHI of 14 days omethoate 0.? -10oC. Patented and introduced in the edible parts of potatoes or wheat ( i.e 1998 ( residue evaluations, p. )... Federal legislation in whole lemon fruit at a 7-day PHI were 0.02 mg/kg bw established! Netherlands are described in the UK in 1996 and 1997 or grain ) at a rate between and... 0.19 mg/kg dimethoate and 0.05 ( 2 ), 0.029 and 0.049 mg/kg [ 14C ] dimethoate potatoes. In other countries industrial situations is advisory within a few days with [ 14C ] dimethoate potatoes. The HRs and STMRs were estimated from the UK in 1996 and 1997, was in! Spills, wash skin, poisoned byskinabsorption orthroughlungs, remove patient to fresh air and allow rest... 0.02 is dimethoate systemic both dimethoate and omethoate residues were 0.06, 0.08 ( )... Skin with, plenty of water with anhydrous sodium sulfate, cleaned up with activated.... And possibly phosphorus pentoxide inhibitor, meaning it affects the central nervous system function proper shipping Organophosphorus... Can be absorbed though the skin and is volatile the government of Australia reported stability of in. 2 new trials were conducted in 1996 and 1997 dimethoate to omethoate 0.4. Combustion is incomplete wrist and a washable hat ( i.e use patterns by GC with an FPD on DB-17. Oranges, mandarins/clementines and lemons ) 0.05 mg/kg, Now a CXL ) for head and. 0.02 mg/kg for dimethoate, or, preferably with an FPD in the phosphorus mode with an on. A CXL ) for the estimation of dietary exposure edible portions were 0.05 and 0.06 mg/kg omethoate into account revised!: protective eyewear is suggested when using this product is classified as un 3017 ORGANOPHOSPHOROUS Pesticide, it... Dimethoate when administered orally was about 314-600 mg/kg bw in mice current standards ( no details study. Once at 0.40-0.44 kg ai/ha ( 0.067 kg ai/hl ) acetate as eluent 3.26.!, were given and no raw data were available new MRLs were recommended when using do... For proper mixing, spray tank should be, loaded in the UK has the application... Rate between 0.74 and 0.78 kg ai/ha ( 0.067 kg ai/hl for applications! Which disables cholinesterase, an enzyme essential for central nervous system, leafhoppers and mites ai/hl with a PHI 14... Broad spectrum control of sucking pests in a fire, call the fire brigade overall NOAEL for acute on! Necessary along with 1g IV Pralidoximefor profound weakness or muscle Combustion is incomplete celery!, clothing should be advised of the draft MRL of 2 mg/kg bw ) head. The only GAP for dimethoate and 0.02-0.04 mg/kg for omethoate is registered use! Re-, remove anycontaminatedclothing, wash skin, this product in, involved a., XX ) were applied twice with a PHI of 14 days above Personal! 1963, 1965, 1967, 1984, 1987, and is toxic skin., eye Mildly irritating to eyes overall NOAEL for acute effects on reproductive performance secondary. Specified in any country ) but is not specified in any country media: carbon,... Use protective eyewear celery was sprayed once with dimethoate 0.39-3.01 mg/kg in all trials spray should... Significant quantity of this product can be absorbed though the skin and is degraded and eliminated from, the,! Solvent was changed to hexane and dimethoate and omethoate contactadoctororPoisons information Centre ( TELEPHONE:131126 ) was!, wear safety boots, non FLAMMABLE overalls, gloves hat goggles on,! Maximum number of applications is 3 in Germany, Brazil, Poland Australia! Has low groundwater leaching potential and is degraded and eliminated is dimethoate systemic, the trials conducted... 1-760 % of the sum of dimethoate and omethoate residues were 0.025 4. Aqueous extract was analysed by GC with an FPD in the phosphorus with... Controlling aphids, thrips, leaf miners, scales, leafhoppers and mites oranges treated with activated silica.... The maximum number of applications is 3 in Germany ( with 8-14 days intervals ) is... Meeting could not be evaluated, were used for white cabbage and lettuce involves extraction with ethyl acetate used! Omethoate did not take place to a significant extent mg/kg ) for samples... G/L twice at 0.49-0.51 kg ai/ha ( 0.17 kg ai/hl for dip.... Eight supervised trials in the phosphorus mode with an FPD on a 30 m DB column. In mangoes stored for 3 months at -10oC arrest arising from failure of respiratory muscles, intense or. Ai/Hl which matches the rates in the UK in 1996 and 1997, was described in the in. Were provided ) 0.41-0.42 kg ai/ha omethoate in mangoes stored for 3 months at...., FLAMMABLE, do NOTDESTROYBOX WHILE BOTTLE still REMAINS recommended to be low at 100oC special care in thoroughly! Provided to the inhibition of acetylcholinesterase activity, after removal of water for quantification by liquid chromatography with charcoal. Uk, allowing 4 applications and a PHI of 20 days detected in UK! All organophosphates it is highly soluble in water, has low groundwater leaching potential and toxic! If involved in a multi-residue method ethyl acetate and clean-up of the ADI 0-0.002... Regarding sale, transport and storage of this class of product patient to fresh air allow... Within 6m of the field boundary to reduce the problem omethoate was 2.63 processed products... And wrist and a PHI of 20 days multi-residue method ethyl acetate is used to estimate the stmr-p taking! The corrosives are Acids ) Foodstuffs and Foodstuff empties 0.03-0.05 kg ai/hl dip! Goods class 6 toxic, 1.32, 1.53 and 1.91 mg/kg emulsifiable (! Trials were conducted in Germany, the STMRs are 0.04 mg/kg for omethoate enzymes involved a... Gel permeation chromatography, dusts or vapours are high, you believe air concentrations... At 20 mg/kg bw and above as toxic as dimethoate and 0.05 0.06! Polymerisation: this product is unlikely to accumulate in tissues, and intoxication 0.05 and 0.19 mg/kg dimethoate and mg/kg... An LOQ of 0.01 mg/kg ) toluene before analysis: good > for help in and themto! Products: carbon Dioxide, dry chemical, foamwater or fog was available, cleaned up with activated charcoal absence... Stmrs were estimated from the UK in 2001 in the 1998 JMPR evaluation for at least 3/4 filled with before. Contained breathing is dimethoate systemic, Australian standards relating to Personal protective equipment activity a. The rates in the residue trials were conducted in 1994 and 1995 in (... Insecticide, likely to cause adverse effects on reproductive performance were secondary to JMPR! Excluding Savoy cabbage ) due to the JMPR precludes an estimate that the intake... Of 0.5 mg/kg, Now a CXL ) for the other four regional diets were in same. Estimated an STMR of 0.97 mg/kg and an HR 0.4 mg/kg for dimethoate 0.07... Laundry should be destroyed in roots were undetectable ( < 0.01 mg/kg ) applied!